Reactive matrices
AssigneeAbbott Laboratories
InventorsJohn Frederick Kennedy, Martin Frank Chaplin
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Abstract
Compositions comprising stable, water-insoluble coatings on substrates to which biologically active proteins can be covalently coupled so that the resultant product has the biological properties of the protein and the mechanical properties of the substrate, for example, magnetic properties of a metal support. The resultant product can be utilized in diagnostic immunoassays as an example, and when the metal substrate is magnetic, the product can be removed from liquid media by a magnetic field ensuring that any washing or incubation process can be finished promptly and efficiently.
Claims7
A composition comprising a water-insoluble metal substrate, the surface of which is coated with a condensation product of an aminobenzoic acid with an aldehyde, which composition is suitable for coupling with an organic compound having biological activity.
Dependencies are inferred from the claim text.