I.sup.125 Imidazole steroid derivatives
AssigneeBeckman Instruments, Inc.
InventorsAlan J. Polito, William S. Knight
Life of this patent
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Abstract
Derivatives of steroids containing an imidazole group specifically bind to the desired antibody without nonspecifically binding to other substances (e.g., proteins in a patient's plasma or serum and the surfaces of reaction vessels).
Claims10
A radioimmunoassay reagent having a structural formula selected from a group consisting of ##STR4## wherein the asterisk (*)indicates radioactive labelling.
A radioimmunoassay method for assaying a steroid selected from a group consisting of cortisol and aldosterone, wherein the improvement comprises using in said method a radio-immunoassay reagent having a structural formula selected from a group consisting of ##STR7## wherein the asterisk (*) indicates radioactive labelling.
Dependencies are inferred from the claim text.