Conversion of aldose to ketose in the presence of oxyanions or mixed oxyanions of tin or germanium
AssigneeImperial Chemical Industries PLC
InventorsSidney Alan Barker, Peter John Somers, Robin Ross Woodbury, Geoffrey Harry Stafford
Life of this patent
Estimating the term…
Abstract
A process for converting aldoses or derivatives thereof into ketoses or derivatives thereof which takes place in the presence of oxyanions or mixed complex oxyanions of germanium or tin which form stronger complexes with the ketoses or derivatives thereof than with the aldoses or derivatives thereof. Using the process the equilibrium position in the aldose-ketose reaction is shifted towards higher proportions of ketose. The process is very applicable to the conversion of glucose to fructose particularly when this conversion takes place enzymatically in the presence of glucose isomerase.
Claims18
A process for the conversion of an aldose or aldose derivative to a ketose or ketose derivative, comprising:
- forming an aqueous solution containing an aldose or aldose derivative and chemically or enzymatically isomerizing said aldose or aldose derivative to a corresponding ketose or ketose derivative in the presence of a complexing reagent which is an oxyanion or mixed complex oxyanion of germanium or tin which forms a stronger complex with the ketose or ketose derivative than with the aldose or aldose derivative,
- maintaining said aqueous solution under aldose to ketose isomerization conditions, and
- recovering a product enriched in said ketose or ketose derivative.
A process for the conversion of an aldose or aldose derivative to a ketose or ketose derivative, comprising:
- forming an aqueous solution containing an aldose or aldose derivative and chemically or enzymatically isomerizing said aldose or aldose derivative to a corresponding ketose or ketose derivative in the presence to a complexing reagent which is an oxyanion or mixed complex oxyanion of germanium which forms a stronger complex with the ketose or ketose derivative than with the aldose or aldose derivative,
- maintaining said solution under aldose to ketose isomerization conditions, and
- recovering a product enriched in the ketose or ketose derivative.
Dependencies are inferred from the claim text.