Pharmaceutical compositions and method of use for prostaglandin 1,11- and 1,15-lactones
AssigneeThe Upjohn Company
InventorGordon L. Bundy
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Abstract
There are described pharmaceutical compositions comprising a lactone which is the 1,9-lactone, the 1,11-lactone, or the 1,15-lactone of a prostaglandin or prostaglandin analog in combination with a pharmaceutical carrier and formulated to deliver said prostaglandin or prostaglandin analog to an esterase-containing tissue area of a mammal. Also disclosed are methods for administering said compositions to a mammal.
Claims38
A pharmaceutical composition comprising an effective amount of a lactone which is the 1,11-lactone or the 1,15-lactone of prostaglandin or prostaglandin analog in combination with a pharamceutical carrier formulated to deliver said prostaglandin or prostaglandin analog to an esterase-containing tissue area of a mammal.
An improved method of administering an effective amount of a prostaglandin or a prostaglandin analog to esterase-containing tissues of a mammal which comprises administering to said mammal a lactone which is the 1,11-lactone or the 1,15-lactone of said prostaglandin or prostaglandin analog in combination with a pharmaceutical carrier.
Dependencies are inferred from the claim text.