Process for the production of 2,5-dichloro-4-bromophenol

A process for the preparation of 2,5-dichloro-4-bromophenol which comprises reacting a mixture of 2,5-dichlorophenol and 2,4-dichlorophenol with about 0.45 to about 0.6 molar amounts of bromine per mole of 2,5-dichlorophenol in a glacial acetic acid reaction medium at a temperature between about 0.degree. C. to 40.degree. C.;

• reacting the resulting mixture with about 0.45 to about 0.6 molar amounts of chlorine per mole of 2,5-dichlorophenol providing the molar amount of chlorine does not exceed that of bromine and thereafter recovering the 2,5-dichloro-4-bromophenol.

A process for the preparation of 4-bromo-2,5-dichlorophenol which comprises reacting a mixture of 2,5-dichlorophenol and 2,4-dichlorophenol, said mixture having at least 55 percent 2,5-dichlorophenol, with an equimolar amount of bromine in a glacial acetic acid reaction medium at a temperature of about 30.degree. C. and thereafter recovering the 4-bromo-2,5-dichlorophenol.

A process for the preparation of 4-bromo-2,5-dichlorophenol which comprises reacting a mixture of 2,5-dichlorophenol and 2,4-dichlorophenol with an equimolar amount of bromine in a glacial acetic acid reaction medium at a temperature of about 30.degree. C. and thereafter recovering the 4-bromo-2,5-dichlorophenol.

A process for the preparation of 4-bromo-2,5-dichlorophenol which comprises reacting a mixture of 2,5-dichlorophenol and 2,4-dichlorophenol obtained by saponifying 1,2,4-trichlorobenzene and distilling 3,4-dichlorophenol from the resulting mixture, with an equimolar amount of bromine in a glacial acetic acid reaction medium at a temperature of about 30.degree. C. and thereafter recovering the 4-bromo-2,5-dichlorophenol.