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US 4,067,892 AGranted
Substituted (4-carboxyphenoxy) phenyl alkane compounds
AssigneeBeecham Group Limited
InventorsDavid Edward Thorne, Keith Howard Baggaley, Brian Morgan
Life of this patent
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Abstract
Pharmaceutical compositions having hypolipidaemic and/or hypoglycaemic activity, contain a substituted (4-carboxyphenoxy) phenyl alkane derivative.
Claims7
A compound of the formula:
- ##STR34## wherein R.sub.1 is a C.sub.1 to C.sub.7 alkyl carbonyl unsubstituted or substituted with carboxyl or C.sub.1 to C.sub.6 alkoxy carbonyl group converted in the human body to a carboxylic acid group;
- R.sub.2 is hydrogen, lower alkyl or lower alkoxyl;
- R.sub.3 is hydrogen, halogen lower alkyl or lower alkoxyl;
- R.sub.4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl, nitro, or a carboxylic ester group;
- or R.sub.3 and R.sub.4 together form the residue of a benzene ring;
- Z is oxygen or sulphur;
- X is straight or branched chain lower alkylene or lower-alkylene-oxy;
- q is zero or an integer from 1 to 12;
- and
- one of m and n is zero and the other is one.
7 more elements
Dependencies are inferred from the claim text.