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US 4,067,891 AGranted
2A,2B-Dihomo-16,16-dimethyl-PGF.sub.2 analogs
AssigneeThe Upjohn Company
InventorGilbert A. Youngdale
Life of this patent
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Abstract
2a,2b-Dihomo-16,16-dimethyl-PGF- and PGE-type compounds are disclosed with processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, reproductive cycle control, and wound healing.
Claims7
An optically active compound of the formula:
- ##STR51## wherein Z is ##STR52## or ##STR53## and wherein R.sub.1 is hydrogen, alkyl of one to 12 carbon atoms, inclusive, ##STR54## or pharmacologically acceptable salts thereof when R.sub.1 is hydrogen.
Dependencies are inferred from the claim text.