Anti-bacterial compositions containing certain 3-nitropyrazoles

An antibacterial composition which comprises a physiologically-acceptable inert carrier and an antibacterially-effective amount of a compound of the formula ##STR18## wherein R represents A. C.sub.3 -C.sub.4 epoxyalkyl,

• B. hydrogen,
• C. c.sub.1 -c.sub.10 alkyl, C.sub.2 -C.sub.10 alkenyl, C.sub.3 -C.sub.10 alkynyl, C.sub.3 -C.sub.10 cycloalkyl, cyclopropylmethyl, C.sub.3 -C.sub.10 cycloalkenyl, C.sub.2 -C.sub.10 alkyl mono- or disubstituted with halo or C.sub.1 -C.sub.3 alkoxy, or C.sub.1 -C.sub.10 alkyl monosubstituted with
• 1. mercapto,
• 2. carboxamido,
• 3. keto oxygen,
• 4. hydroxy,
• 5. phthalimido,
• 6. C.sub.1 -C.sub.3 alkylthio,
• 7. C.sub.1 -C.sub.3 alkylsulfonyl,
• 8. C.sub.1 -C.sub.3 alkanoyl,
• 9. phenyl,
• 10. phenyl monosubstituted with
• a. C.sub.1 -C.sub.3 alkyl,
• b. C.sub.1 -C.sub.3 haloalkyl,
• c. hydroxy, or
• d. halo, ##STR19## wherein R.sup.1 represents a. C.sub.1 -C.sub.3 alkyl,
• b. C.sub.1 -C.sub.3 alkoxy,
• c. C.sub.1 -C.sub.3 haloalkyl,
• d. amino,
• e. C.sub.3 -C.sub.6 cycloalkyl,
• f. phenoxy,
• g. phenyl, or
• h. phenyl monosubstituted with
• 1. C.sub.1 -C.sub.3 alkyl,
• 2. C.sub.1 -C.sub.3 haloalkyl,
• 3. halo, or
• 4. hydroxy, or
• 12. cyano, or
• D. 4-nitrophenyl, 5-nitro-2-thiazolyl, or 3-nitro-2-pyridyl;
• and
• X represents
• A. 5-methylamino-1,3,4-thiadiazol-2-yl,
• B. cyano, ##STR20##
• wherein R.sup.2 represents 1. hydrogen, or
• 2. C.sub.1 -C.sub.6 alkyl;
• or ##STR21## wherein R.sup.3 represents C.sub.1 -C.sub.6 alkyl;
• provided that a C.sub.1 alkyl R group is substituted only with phenyl or substituted phenyl.