Back to results
US 4,066,767 AGranted
8-(1H-Tetrazol-5-yl)-11H-pyrido[2,1-b]quinazolin-11-ones and method of treating bronchial asthma using them
AssigneeWarner-Lambert Company
InventorsCharles F. Schwender, Brooks R. Sunday
Life of this patent
Estimating the term…
Abstract
The present invention relates to 8-(1H-tetrazol-5-yl)-11H-pyrido[2,1-b]quinazolin-11-ones having the following structure: ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen, alkyl, alkyloxy, halogen, hydroxy and methylenedioxy; R.sub.3 is carboxamido, cyano or 5-tetrazolyl groupings and the pharmaceutically acceptable salts of acids and bases thereof. These compounds exhibit anti-allergic properties and are useful as anti-asthmatic agents.
Claims7
A compound of the formula:
- ##STR4## wherein R.sub.1 and R.sub.2 are hydrogen, halogen, hydroxy, methylenedioxy or lower alkyl or alkoxy of 1 to 4 carbons;
- R.sub.3 is 5-tetrazolyl and the pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.