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US 4,064,341 AGranted
Nogalamycinic acid and derivatives thereof
AssigneeThe Upjohn Company
InventorsPaul F. Wiley, Jian L. Johnson
Life of this patent
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Abstract
Novel antibiotic, nogalamycinic acid (U-51,205) prepared by the chemical modification of the known antibiotic nogalamycin. Nogalamycinic acid is active against various microorganisms, for example, Mycobacterium avium, Bacillus subtilis, Lactobacillus casei, Staphylococcus aureus, and Sarcina lutea. Thus, nogalamycinic acid can be used to inhibit the growth of the above microorganisms in various environments.
Claims2
Nogalamycinic acid, a compound having the following structure:
- ##STR3## and non-toxic alkali and alkaline earth metal salts thereof.
Acylates of nogalamycinic acid wherein said acyl group consists of hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive;
- halo-, nitro-, amino-, cyano-, and lower alkoxy-substituted hydrocarbon carboxylic acid acyl of from 2 to 18 carbon atoms, inclusive.
Dependencies are inferred from the claim text.