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US 4,064,273 AGranted
Treating lipidemia with substituted diphenyl ether halides and compositions thereof
AssigneeSandoz Ltd.
InventorFaizulla G. Kathawala
Life of this patent
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Abstract
Hypolipidemic agents of the formula: ##STR1## wherein R is branched lower alkyl, R' is hydrogen or alkyl, X is halo, and n is 2.
Claims9
A pharmaceutical composition in unit dosage form for treating lipidemia in mammals comprising an inert pharmaceutically acceptable carrier and from 150 to 2000 milligrams of a compound of the formula:
- ##STR5## wherein R is branched alkyl of 3 to 5 carbon atoms,
- R' is hydrogen or alkyl of 1 to 4 carbon atoms,
- X is halo of atomic weight of from 18 to 80, and n is 2,
- with the proviso that the R groups are not in ortho position with respect to each other.
1 more element
A method for treating lipidemia in mammals comprising administering to mammals in need of such treatment a hypolipidemic effective amount of a compound of the formula ##STR7## wherein R is branched alkyl of 3 to 5 carbon atoms, R' is hydrogen or alkyl of 1 to 4 carbon atoms,
- X is halo of atomic weight of from 18 to 80, and
- n is 2,
- with the proviso that the R groups are not in ortho position with respect to each other.
Dependencies are inferred from the claim text.