Dosage regimen

Abstract

An improved dosage regimen for the administration of the pharmacologically acceptable salts or esters of a compound of the formula: ##STR1## wherein X and Y can be the same or different and are selected from the group consisting of hydrogen, alkyl of from one to six carbon atoms, inclusive, cycloalkyl of five or six carbon atoms, inclusive, phenyl, hydroxyl, alkoxy having from one to three carbon atoms, inclusive, halogen, trifluoromethyl, cyano, carboxyamide and --CO.sub.2 H; Z is selected from the group consisting of hydrogen, alkyl from one to three carbon atoms, inclusive, and phenyl and provided when X is chloro at least one of Y and Z are other than hydrogen consisting of the initial administration of a priming dose (high) and thereafter administering a maintenance (low) dose of from 1/5th to 1/1000th of the priming dose, the maintenance doses being continually administered every 4 to 12 hours or as needed. The priming dose is re-administered followed by the maintenance doses whenever a 48 hour period without dosage administration occurs.

Dependencies are inferred from the claim text.