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US 4,064,165 AGranted
15-Ethynyl-PGE.sub.1
AssigneeAmerican Home Products Corporation
InventorGeorge E. M. Husbands
Life of this patent
Estimating the term…
Abstract
7-(2.beta.-[(3S)-3-Ethynyl-3-hydroxy-trans-1-octenyl]-3.alpha.-hydroxy-5-ox o-1.alpha.-cyclopentyl)-cis-5-heptenoic acid, 2.beta.-[(3S)-3-ethynyl-3-hydroxy-trans-1-octenyl]-3.alpha.-hydroxy-5-oxo- 1.alpha.-cyclopentane heptanoic acid, related compounds, and intermediates thereto are disclosed. The final products have activity as bronchodilators and in reducing gastric secretion.
Claims3
A compound of the formula:
- ##STR4## wherein A is a single bond;
- and R is hydrogen, alkyl of from 1 up to about 6 carbon atoms, alkali metal, or a pharmacologically acceptable cation derived from ammonia or a basic amine.
Dependencies are inferred from the claim text.