US 4,064,133 A · Cyclohexenone derivatives

Abstract

Novel cyclohexenone derivatives, which are shown by the general formula ##STR1## wherein each of R.sup.1 and R.sup.2 represents a hydrogen atom, lower alkyl or phenyl group; one of R.sup.3 and R.sup.4 represents a hydrogen atom or lower alkyl group, and the other represents an unsubstituted or substituted phenyl, lower alkyl or aralkyl group, or R.sup.3 and R.sup.4, taken together with the adjacent nitrogen atom, form a 5 to 6-membered heterocyclic ring; one of R.sup.5 and R.sup.6 represents a hydrogen atom or lower alkyl group, and the other represents a lower alkyl, phenyl or aralkyl group, or R.sup.5 and R.sup.6, taken together with the adjacent nitrogen atom, form an unsubstituted or substituted 5 to 6-membered heterocyclic ring, and their pharmaceutically acceptable salts, useful medicines such as analgesics.

Claims12

Dependent claims

A member selected from the group consisting of a compound of formula ##STR4## wherein each of R.sup.1 and R.sup.2 represents hydrogen, or methyl or when one of R.sup.1 or R.sup.2 is hydrogen the other may represent phenyl, one of R.sup.3 and R.sup.4 represents hydrogen, alkyl of 1 to 6 carbon atoms, and the other represents alkyl of 1 to 6 carbon atoms, benzyl, phenethyl, phenyl or phenyl mono-substituted by a member of the group consisting of alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms, halogen, nitro and hydroxy,

R.sup.5 and R.sup.6 represent piperidino, or piperidino monosubstituted by a member of the group consisting of alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms, halogen, and hydroxy, with the proviso that the alkoxy, halogen and hydroxy substituent is in the 4-position of the piperidino nucleus and a pharmaceutically acceptable salt thereof.

Dependencies are inferred from the claim text.

Cyclohexenone derivatives

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Cyclohexenone derivatives

Life of this patent

Abstract

Claims12