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US 4,064,120 AGranted
3,3-Dichloro-2-azetidinone derivatives having antiinflammatory activity
AssigneeE. R. Squibb & Sons, Inc.
InventorsJohn Krapcho, Chester F. Turk
Life of this patent
Estimating the term…
Abstract
Compounds having the formula ##STR1## wherein R.sub.1 is alkyl, cycloalkyl or aryl; R.sub.2 is dialkylamino or a nitrogen containing heterocyclic group; A.sub.1 is a saturated bond or an alkylene group having 1 to 4 carbon atoms; and A.sub.2 is an alkylene group having 2 to 5 carbon atoms; have antiinflammatory activity.
Claims10
A compound having the formula ##STR5## or a pharmaceutically acceptable salt thereof, wherein R.sub.1 is alkyl, cycloalkyl or aryl;
- R.sub.2 is dialkylamino;
- A.sub.1 is a saturated bond or an alkylene group having 1 to 4 carbon atoms;
- and A.sub.2 is an alkylene group having 2 to 5 carbon atoms;
- wherein aryl is phenyl or phenyl mono substituted with a halogen, alkyl, alkoxy, trifluoromethyl, or nitro group;
- alkyl and alkoxy are groups having 1 to 6 carbon atoms;
- and cycloalkyl is a group having 3 to 7 carbon atoms.
3 more elements
Dependencies are inferred from the claim text.