Amino substituted arylthio-alkanoic acids having hypolipidemic activity
AssigneeThe Dow Chemical Company
InventorsEugene R. Wagner, Bobbie J. Allen
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Abstract
This invention relates to novel compounds and compositions of amino substituted arylthio-alkanoic acid, the corresponding pharmaceutically-acceptable salts and the esters thereof. The invention also relates to methods for reducing plasma lipid levels in animals using the compounds of the present invention.
Claims10
A compound of the formula ##STR4## wherein R.sub.1 represents hydrogen
- and R.sub.2 and R.sub.3 independently represent hydrogen or an alkyl having from 1 to about 5 carbon atoms
- and the pharmaceutically acceptable salts thereof.
A hypolipidemic composition comprising a suitable pharmaceutical carrier and a hypolipidemically effective amount of a compound having the formula ##STR5## wherein R.sub.1 represents hydrogen
- and R.sub.2 and R.sub.3 independently represent hydrogen or an alkyl having from 1 to about 5 carbon atoms
- and the pharmaceutically acceptable salts thereof.
A method for lowering elevated serum lipids in a mammal which comprises administering internally to the mammal a hypolipidemically effective amount of a compound having the formula ##STR6## wherein R.sub.1 represents hydrogen
- and R.sub.2 and R.sub.3 independently represent hydrogen or an alkyl having from 1 to about 5 carbon atoms
- and the pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.