N-formyl-2,3,5,6-dibenzobicyclo[5.1.0]octan-4-methylamine
AssigneeMerck & Co., Inc.
InventorDavid C. Remy
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Abstract
The new 4-aminomethyldibenzobicyclo[ 5.1.0] octane compounds of the present invention are prepared from the corresponding 4-halo compounds by reaction with a metal cyanide to produce the corresponding 4-cyano compound, which is reduced with an alkali metal aluminum hydride to produce the desired 4-aminomethyl compound. These new aminomethyldibenzobicyclo[ 5.1.0] octane compounds are converted to the corresponding secondary and tertiary amino derivatives. These new compounds are useful as antiarrhythmic agents and can be used to overcome cardiac irregularities.
Claims2
A compound of the formula:
- ##STR3## and the non-toxic pharmaceutically acceptable acid addition salts thereof.
N-Formyl-2,3,5,6-dibenzobicyclo[5.1.0]octan-4-methylamine.
Dependencies are inferred from the claim text.