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US 4,062,868 AGranted
Synthesis of biotin
AssigneeHoffmann-La Roche Inc.
InventorsPasquale Nicholas Confalone, Elizabeth Dianne Lollar, Giacomo Pizzolato, Milan Radoje Uskokovic
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Abstract
A novel process for the preparation of biotin is disclosed wherein said process employs inexpensive starting materials and reagents resulting in the obtention of biotin devoid of the biologically inactive stereoisomers.
Claims3
A compound of the formula ##STR23## wherein Q is --CO.sub.2 R.sub.4, where R.sub.4 is lower alkyl the racemates and optical antipodes thereof.
Dependencies are inferred from the claim text.