Hydroxy pyrimido compounds

A compound of the formula ##STR81## and tautomer thereof, wherein m is 1 or 2;

• when m is 1, R occupies either position-4 or -5 of the starting 2-aminopyrimidine, but when R is halogen, it occupies only position -5;
• when m is 2, the two R's occupy the 4- and 5-positions of the starting 2-aminopyrimidine, but only one of the two R-substituents can be halogen and it must occupy the 5-position;
• R is the same or different and is hydrogen, F, Cl, Br, alkyl of from 1 to 4 carbons except where both alkyls are t-butyl, benzyl, phenyl, or mono-substituted phenyl wherein the substituent is F, Cl, Br, I, alkyl of from 1 to 4 carbons, alkoxy of from 1 to 4 carbons, or trifluoromethyl;
• R' is hydrogen, F, Cl, Br, CF.sub.3, alkyl of from 1 to 4 carbons, or dialkylamidosulfonyl wherein each alkyl radical has from 1 to 4 carbons;
• n is 0 or 1;
• R" is hydrogen or alkyl of from 1 to 4 carbons;
• Z is S or SO.sub.2,
• and pharmaceutically acceptable acid additions salts thereof.