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US 4,062,783 AGranted
15-Ethynyl substituted prostanoic acids
AssigneeAmerican Home Products Corporation
InventorDonald P. Strike
Life of this patent
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Abstract
9-Oxo-15-substituted prostanoic acids, and intermediates for their preparation and for the preparation of other known prostaglandins are disclosed. The final products have bronchodilatory activity.
Claims3
A compound of the formula:
- ##STR5## wherein R.sup.1 is hydrogen, alkyl of from 1 to about 6 carbon atoms, alkali metal, or a pharmacologically acceptable cation derived from ammonia or a base amine.
7-[2.beta.-(3-Ethynyl- 3-hydroxy-trans-1-octenyl)-5-oxo-1.alpha.-cyclopentyl]-cis-5-heptenoic acid.
A compound of the formula:
- ##STR6## wherein R.sup.1 is alkyl of from 1 to about 6 carbon atoms, alkali metal, or a pharmacologically acceptable cation derived from ammonia or a basic amine.
Dependencies are inferred from the claim text.