Derivatives of 7-(cyclized)phenylglycyl-3-triazolo-thio methyl cephalosporin
AssigneeBristol-Myers Company
InventorsMurray A. Kaplan, William J. Gottstein, Alphonse P. Granatek
Life of this patent
Estimating the term…
Abstract
Compounds of the formula ##STR1## wherein A is hydrogen, hydroxy, methyl or methoxy, R.sup.1 is hydrogen, sodium or potassium, and R.sup.2 is 1,2,3-triazol-5-yl, such group being unsubstituted or substituted with one or two lower alkyl groups of one to four carbon atoms are prepared by reacting the appropriate aldehyde with the corresponding amphoteric cephalosporin. A preferred product has the structure ##STR2##
Claims16
A compound of the formula ##STR15## wherein A is hydrogen, hydroxy, methyl or methoxy,
- R.sup.1 is hydrogen, sodium or potassium, and
- R.sup.2 is 1,2,3-triazol-5-yl, such group being unsubstituted or substituted with one or two lower alkyl groups of one to four carbon atoms.
A compound of the formula ##STR16## wherein A is hydrogen, hydroxy, methyl or methoxy, and
- R.sup.1 is hydrogen, sodium or potassium.
A compound of the formula ##STR17## wherein R.sup.1 is hydrogen, sodium or potassium.
A compound of the formula ##STR18## wherein A is hydrogen, hydroxy, methyl or methoxy, and
- R.sup.1 is hydrogen, sodium or potassium.
A compound of the formula ##STR20## wherein A is hydrogen, hydroxy, methyl or methoxy, and
- R.sup.1 is hydrogen, sodium or potassium.
Dependencies are inferred from the claim text.