Modified, grafted mineral carriers
AssigneeRhone-Poulenc Industries
InventorsHonore Mazarguil, Francois Meiller, Pierre Monsan
Life of this patent
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Abstract
The invention concerns mineral carriers carrying modified silicon grafts. They comprise mineral carriers grafted by silicon derivatives with aromatic amino substituents, modified by substituted or unsubstituted adenine radicals. The carriers are used in chromatography and more particularly in affinity chromatography for the purification of enzymes.
Claims7
A method of preparing carriers comprising grafting onto a mineral carrier, a silicon derivative, diazotizing the grafted mineral carrier, and then fixing adenine or its derivative onto the diazotized grafted mineral carrier in which the silicon derivative to be grafted is of the general formula ##STR4## wherein A, B and C, which may be similar or different, are selected from the group consisting of methoxy, ethoxy, methyl or ethyl, provided that at least one of them is reactive with an Oh group in the mineral carrier, n being a whole number with a value from 2 to 4.
Mineral carriers grafted with silicon derivatives having aromatic amino substituents in which the silicon derivative has the general formula ##STR5## wherein A, B and C, which may be similar or different, are selected from the group consisting of methoxy, ethoxy, methyl or ethyl, provided that at least one of them is reactive with an OH group in the mineral carrier, n being a whole number with a value from 2 to 4, and said grafts modified by substituted or unsubstituted adenine radicals.
Dependencies are inferred from the claim text.