Derivatives of the 1,2-diarylethylene and pharmaceutical compositions thereof
AssigneeHoechst Aktiengesellschaft
InventorsHermann Teufel, Wilhelm Bartmann, Ernold Granzer, Josef Musil
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Abstract
The invention relates to derivatives of 1,2-diarylethylene and to a process for their preparation. The compounds have valuable pharmaceutical properties and may be used as medicaments.
Claims3
A 1,2-diaryl-ethylene of the formula ##STR5## wherein Hal is chlorine or bromine and Ar and Ar' are each phenyl substituted by one or two members selected from the group consisting of lower alkyl, lower alkoxy and halogen, or one of Ar and Ar' is phenyl and the other is substituted phenyl.
A pharmaceutical composition comprising, in combination with a pharmaceutical carrier, an effective ingredient which is a compound of the formula ##STR6## wherein Hal is chlorine or bromine and Ar and Ar', which are the same or different, are phenyl or phenyl substituted by one or two members selected from the group consisting of lower alkyl, lower alkoxy and halogen.
A method for treating disorders of purine metabolism, hyperlipidemiae, or both conditions, in a patient suffering therefrom, which method comprises administering an effective amount of a compound of the formula ##STR7## wherein Hal is chlorine or bromine and Ar and Ar', which are the same or different, are phenyl or phenyl substituted by one or two members selected from the group consisting of lower alkyl, lower alkoxy and halogen.
Dependencies are inferred from the claim text.