Control of lactic acidosis in ruminants
AssigneeMerck & Co., Inc.
InventorsLarry A. Muir, Albert Barreto
Life of this patent
Estimating the term…
Abstract
The nutritional disease, lactic acidosis, is successfully prevented by orally administering to the animal an effective amount of a sulfur-containing peptide antibiotic. In particular thiopeptin and thiostrepton are particularly effective sulfur-containing peptide antibiotics useful against lactic acidosis.
Claims12
A method for the prevention of lactic acidosis in ruminants and for shortening the period of adaptation of said ruminants to a high energy feed from a low energy roughage feed wherein said low energy roughage feed has an energy content of less than 110 megacalories per 100 kg. of feed and said high energy feed has an energy content of 110 or more megacalories per 100 kg. of feed, which comprises administering to said ruminant said high energy feed and an effective amount of a sulfur-containing peptide antibiotic with a molecular weight in excess of 900.
A method for the prevention of lactic acidosis in ruminants and for shortening the period of adaptation of said ruminants to a high energy feed following a period of starvation which comprises administering to a ruminant which has been deprived of feed for a period in excess of 6 hours, a high energy medicated feed comprising a feed ration having an energy content of 110 or more megacalories per 100 kg. of feed and an effective amount of a sulfur-containing peptide antibiotic with a molecular weight in excess of 900.
A method for the prevention of lactic acidosis in ruminants and for shortening the period of adaptation of said ruminants to a higher energy feed from a lower energy feed wherein said lower energy feed has an energy content of at least 110 megacalories per 100 kg. of feed and said higher energy feed has an energy content of 10 or more megacalories per 100 kg. higher than said lower energy feed which comprises including in said higher energy feed an effective amount of a sulfur-containing peptide antibiotic having a molecular weight in excess of 900.
Dependencies are inferred from the claim text.