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US 4,061,656 AGranted
Polyene compounds
AssigneeHoffmann-La Roche Inc.
InventorsMichael Josef Klaus, Beverly Ann Pawson
Life of this patent
Estimating the term…
Abstract
Novel 9-substituted or unsubstituted thienyl-3,7-dimethyl-nona-2,4,6,8-tetraene derivatives, useful as antitumor agents as well as processes for their preparation and novel intermediates are disclosed.
Claims12
A compound represented by the formula ##STR23## wherein one of R.sub.1 or R.sub.2 is ##STR24## and the other of R.sub.1 or R.sub.2 and R.sub.3 and R.sub.4 are hydrogen, lower alkyl, nitro, and R.sub.5 is carboxyl, alkoxycarbonyl, alkenoxycarbonyl, and alkynoxycarbonyl.
Dependencies are inferred from the claim text.