US 4,061,642 A · 2,4,6-Trisubstituted-3-pyridine carboxamides

Abstract

Compounds of the formula ##STR1## wherein X is aliphatic, cycloaliphatic, aromatic, aralkyl, hetaryl, hetarylalkyl or hydrogen; Y is aliphatic, aromatic, aralkyl, --COOR.sub.1, --COR.sub.2, ##STR2## --SO.sub.2 R.sub.2, ##STR3## --CN, --NH.sub.2, --NO, --NO.sub.2 or hydrogen with the proviso that when Y is hydrogen, X is other than hydrogen; Z.sub.1 is cyano, ##STR4## --NH--OR.sub.10, ##STR5## --OR.sub.12, --SR.sub.12 or --SO.sub.2 R.sub.12 and Z.sub.2 is chlorine, bromine, cyano, hydroxy, mercapto, --OR.sub.12, --SR.sub.12, --SO.sub.2 R.sub.12, ##STR6## --NH--OR.sub.10 or ##STR7## R.sub.1 is aliphatic; R.sub.2 is aliphatic, cycloaliphatic, aromatic, aralkyl or heterocyclic; R.sub.3 and R.sub.4 when taken separately are hydrogen, aliphatic, cycloaliphatic, aromatic or aralkyl; R.sub.3 and R.sub.4 when taken together with the nitrogen atom to which they are attached form a heterocyclic moiety; R.sub.5 and R.sub.6 when taken separately are aliphatic, aromatic, aralkyl, heterocyclic or hydrogen; R.sub.5 and R.sub.6 when taken together with the nitrogen atom to which they are attached are heterocyclic; R.sub.7 is hydrogen, aliphatic or aromatic; R.sub.8 and R.sub.9 are aliphatic or aromatic, R.sub.10 is hydrogen, aliphatic or aralkyl, R.sub.11 is aliphatic and R.sub.12 is aliphatic, aromatic or aralkyl; R.sub.10 and R.sub.11 when taken together with the nitrogen atom to which they are attached are heterocyclic.

Claims3

Dependent claims

A compound of the formula ##STR565## wherein X is alkyl having 1 to 6 carbon atoms, alkenyl having 2 to 6 carbon atoms, cycloalkyl having 3 to 8 carbon atoms, phenyl, benzyl, phenethyl or hydrogen;

Z.sub.1 is ##STR566## --NH--OR.sub.10 or ##STR567## R.sub.3 and R.sub.4, when taken separately, are alkyl having 1 to 6 carbon atoms, cycloalkyl having 3 to 8 carbon atoms, phenyl, benzyl, phenethyl or hydrogen;
R.sub.3 and R.sub.4, when taken together with the nitrogen atom to which they are attached form an ethyleneimino radical;
R.sub.5 and R.sub.6 are hydrogen, alkyl having 1 to 6 carbon atoms, hydroxyalkyl having 1 to 6 carbon atoms, cycloalkyl having 3 to 8 carbon atoms, methoxyalkyl or ethoxyalkyl having 1 to 6 carbon atoms in the alkyl moiety, benzyl or phenethyl;
R.sub.10 is alkyl having 1 to 6 carbon atoms, benzyl or phenethyl;
R.sub.11 is alkyl having 1 to 6 carbon atoms and R.sub.12 is alkyl having 1 to 6 carbon atoms, alkenyl having 2 to 6 carbon atoms, cycloalkyl having 3 to 8 carbon atoms, phenyl, benzyl or phenethyl.

2 more elements

Dependencies are inferred from the claim text.

2,4,6-Trisubstituted-3-pyridine carboxamides

Life of this patent

2,4,6-Trisubstituted-3-pyridine carboxamides

Life of this patent

Abstract

Claims3