3-Carbamylbenzyl-7-(phenylglycyl)amino cephalosporin derivatives
AssigneeBeecham Group Limited
InventorBrian George James
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Abstract
Antibacterial 3-carbamoylbenzyl cephems and 3-(carbamoylpyridylmethyl) cephems, pharmaceutically acceptable salts and in vivo hydrolyzable esters thereof; pharmaceutical compositions containing antibacterially effective amounts of such cephems and intermediates therefor. Minimum inhibitory concentrations against various bacteria are given. The cephems and compositions containing the same are suitable for administration in conventional forms to humans.
Claims15
A compound of the formula:
- ##STR29## pharmaceutically acceptable salt thereof wherein Y is H or OH and Z is NH.sub.2 or OH.
A method of treating bacterial infections in humans which comprises administering to a human in need thereof an antibacterially effective amount of a compound of the formula ##STR30## or a pharmaceutically acceptable salt thereof wherein Y is H or OH and Z is NH.sub.2 or OH.
Dependencies are inferred from the claim text.