Tablets coated with aqueous resin dispersions
AssigneeBoehringer Mannheim GmbH
InventorsGregor Groppenbacher, Peter Rieckmann, Werner Rothe
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Abstract
Coated tablets are prepared by applying to a core of active material, at least one layer of a coating composition made up of a film forming aqueous synthetic resin dispersion and from 2-50% by weight of a water or alkaline soluble material and thereafter permitting the coating composition layer to dry. The resulting coated tablet has a core surrounded by a continuous porous matrix of synthetic resin formed from the aqueous dispersion which is insoluble in water and insoluble in the gastrointestinal tract. The pores of the continuous resin matrix are filled with a discontinuous particulate material which is water or alkaline soluble. The coated tablet initially is air and moisture tight.
Claims19
Coated tablet comprising a core of active material soluble in the gastrointestinal tract and a coating surrounding said core said coating comprising a continuous porous matrix of a synthetic resin insoluble in the gastrointestinal tract and a water or alkaline soluble material in the pores of said matrix, said coating being formed by applying to said core at least one layer of a coating composition of a film forming aqueous zynthetic resin dispersion with a resin content between 30 and 60% by weight and from 2 to 50% by weight of said water or alkaline soluble material and permitting said coating composition layer to dry, said coated tablet being initially air and moisture tight.
Dependencies are inferred from the claim text.