US 4,060,540 AGranted

Novel 3-triphenylmethoxy-1-alkynes, 3-triphenyl-methoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates

AssigneeAmerican Cyanamid Company

InventorsKarel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss

Life of this patent

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Abstract

This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.

Claims2

Dependent claims

Compounds of the formula:

##STR36## wherein m is an integer having the value of 4 to 8, inclusive, and R' are alkyl groups having from 1 to 10 carbon atoms and are not necessarily the same.

Dependencies are inferred from the claim text.

Facts

Application: 05/739,174Filed 5 Nov 1976 · division
Priority: 27 Apr 1973
Granted: 29 Nov 1977
Term ends: Not estimatedThe source records don’t support an estimate.

Classification5 codes

C07D 309/38
With oxygen atoms directly attached to ring carbon atoms: one oxygen atom in position 2 or 4, e.g. pyrones
C07C 405/00
Compounds containing a five-membered ring having two side-chains in ortho position to
C07D 309/12
Oxygen atoms: only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
C07D
Heterocyclic compounds

Family

Serial355,350Parent of this division · filed 27 Apr 1973
Serial613,776Parent of this division · filed 18 Sep 1975
US 4,007,210 AParent of this division
US 3,932,479 AParent of this division
US 4,060,540 AThis patent

From the US filing history. Foreign family members aren’t listed.

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