9-Deoxy-9-methylene-PGF compounds

A prostaglandin analog of the formula:

• ##STR41## wherein Y.sub.1 is trans--CH.dbd.CH--, --C.tbd.C--, or --CH.sub.2 CH.sub.2 --;
• wherein M.sub.1 is ##STR42## wherein R.sub.5 is hydrogen or methyl;
• wherein L.sub.1 is ##STR43## or a mixture of ##STR44## wherein R.sub.3 and R.sub.4 are hydrogen, methyl, or fluoro, being the same or different, with the proviso that one of R.sub.3 and R.sub.4 is fluoro only when the other is hydrogen or fluoro;
• wherein Z.sub.7 is
• 1. cis--CH.dbd.CH--CH.sub.2 --(CH.sub.2).sub.g --CH.sub.2 --,
• 2. cis--CH.dbd.CH--CH.sub.2 --(CH.sub.2).sub.g --CF.sub.2 --,
• 3. cis--CH.sub.2 --CH.dbd.CH--(CH.sub.2).sub.g --CH.sub.2 --,
• 4. --(ch.sub.2).sub.3 --(ch.sub.2).sub.g --CH.sub.2 --,
• 5. --(ch.sub.2).sub.3 --(ch.sub.2).sub.g --CF.sub.2 --,
• 6. --ch.sub.2 --o--ch.sub.2 --(ch.sub.2).sub.g --CH.sub.2 --,
• 7. --c.tbd.c--ch.sub.2 --(ch.sub.2).sub.g --CH.sub.2 --, or
• --CH.sub.2 --C.tbd.C--(CH.sub.2).sub.g --CH.sub.2 --,
• wherein g is one, 2, or 3;
• wherein m is one to 5, inclusive;
• and
• wherein R.sub.1 is hydrogen, alkyl of one to 12 carbon atoms, inclusive, cycloalkyl of 3 to 10 carbon atoms, inclusive, aralkyl of 7 to 12 carbon atoms, inclusive, phenyl, phenyl substituted with one, two, or three chloro or alkyl of one to 3 carbon atoms, inclusive, or a pharmacologically acceptable cation.