US 4,060,530 AGranted

Clavulanic acid amides

AssigneeBeecham Group Limited

InventorsThomas Trefor Howarth, John Barry Harbridge

Life of this patent

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Amides of the compound of the formula ##STR1## are useful for their .beta.-lactamase inhibitory activity.

Dependent claims

A compound of the formula (II):

##STR28## wherein R.sub.1 is hydrogen, alkyl of 1 to 4 carbon atoms, CF.sub.3 CH.sub.2, phenyl, tolyl or benzyl and R.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms.

Dependencies are inferred from the claim text.

A61K 31/43
Condensed with heterocyclic ring systems: compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring…
A61K 31/42
Having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole: oxazoles
A61P 31/04
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antibacterial agents
C07D 499/00
Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a

No related US applications are recorded in the indexed filing history.

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