Process for the microbial production of L-serine using pseudomonas Sp. DSM 672
AssigneeGesellschaft fur Biotechnologische Forschung mbH (GBF)
InventorsFritz Wagner, Hermann Sahm, Walter Hartmut Keune
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Abstract
L-serine is produced by aerobic cultivation of Pseudomonas Sp. DSM 672, or mutants thereof, in a nutrient medium including methanol and glycine.
Claims14
A process for the production of L-serine in which methanol and glycine are mixed with a submerse culture containing inorganic nutrients and the bacterium Pseudomonas sp. DSM 672 and/or L-Serine accumulating mutants of this bacterium in a reactor supplied with a gas which is air or oxygen-enriched air at a pH in the range 6.0 to 9.0 and at a temperature in the range 20.degree. to 40.degree. C, the mixture is allowed to react, the resulting cell mass is separated from the culture filtrate and the L-serine is isolated from the culture filtrate.
Dependencies are inferred from the claim text.