Process for freezing blood platelets
AssigneeThe Community Blood Council of Greater New York, Inc.
InventorsArthur W. Rowe, George Dayian
Life of this patent
Estimating the term…
Abstract
A frozen proteinaceous mass comprising blood platelets coated with glycerol-glucose, the frozen mass prepared by a process comprising: A. contacting blood platelets with an aqueous saline solution containing 4 to 7 weight percent glycerol and glucose 2 to 6 weight percent in an at least 5 : 1 volume to volume solution : platelet ratio; B. removing supernatant liquid; C. concentrating platelets to about 20 mg platelets protein per ml. D. thereafter freezing the platelets at a rate of at least 20.degree. C per minute.
Claims13
A process for preserving blood platelets which comprises:
- A. contacting said platelets with an aqueous saline solution containg 4 to 7 weight percent glycerol and 2 to 6 weight percent glucose, the glycerol being employed in at least a 5 :
- 1 volume solution to volume platelet ratio;
- B. removing supernatant liquid;
- C. concentrating platelets to about 20 mg platelet protein/ml;
- D. thereafter freezing said platelets at a rate of at least 20.degree. C per minute.
A process for preserving blood platelets which comprises:
- A. contacting said platelets with an aqueous saline solution containing 4 to 7 weight percent glycerol and 2 to 6 weight percent glucose in at least 5 :
- 1 volume solution to volume platelet ratio;
- B. removing supernatant liquid;
- C. concentrating platelets to about 10-20 mg platelet protein per ml;
- and
- D. thereafter freezing said platelets at a rate of at least 20.degree. C per minute.
A process for preserving blood platelets which comprises:
- A. contacting said platelets with an aqueous saline solution containing 4 to 7 weight percent glycerol and 2 to 6 weight percent glucose in at least 5 :
- 1 volume solution to volume platelet ratio;
- B. removing supernatant liquid;
- C. concentrating said platelets;
- and
- D. thereafter freezing said platelets at a rate of at least 20.degree. C per minute.
A process for preserving blood platelets which comprises:
- A. contacting said platelets with an aqueous saline solution containing 4 to 7 weight percent glycerol in at least 5 :
- 1 volume solution to volume platelet ratio;
- B. removing supernatant liquid;
- and
- C. thereafter freezing said platelets at a rate of at least 20.degree. C per minute.
Dependencies are inferred from the claim text.