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US 4,059,687 AGranted
Ester substituted dibiguanides and non-toxic antimicrobial compositions thereof
AssigneeColgate-Palmolive Company
InventorRobert Andrew Bauman
Life of this patent
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Abstract
Novel dibiguanides containing an ester substituent on the terminal phenyl radical and free of the presence of, or the tendency to form, toxic substances; the process of preparing said dibiguanides, and compositions containing an effective antimicrobial amount of said dibiguanides admixed with a pharmaceutical carrier.
Claims9
A dibiguanide compound free of toxic substances having the structural formula:
- ##STR7## wherein one of A and B is hydrogen and the other is the ester radical ##STR8## and R is an alkyl group containing 1-8 carbon atoms and n is an integer from 5 to 12;
- and the acid salts thereof selected from the group consisting of HCl, HBr, HI, HF, H.sub.2 SO.sub.4, CH.sub.3 COOH, gluconic acid, H.sub.2 PO.sub.3 F and H.sub.3 PO.sub.4.
Dependencies are inferred from the claim text.