Substituted imidazole compounds and therapeutic compositions therewith
AssigneeMerck & Co., Inc.
InventorJohn J. Baldwin
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Abstract
Substituted imidazole compounds which are useful as anti-hypertensive agents or as xanthine oxidase inhibitors.
Claims20
A compound of the formula ##STR6## wherein R.sub.1 is hydrogen or alkyl containing 1 to 3 carbon atoms;
- R.sub.2 is halogen;
- and
- R.sub.3 is halogen or --CF.sub.3
- or a pharmaceutically acceptable salt thereof.
A pharmaceutical composition for treating hypertension comprising an inert pharmaceutically acceptable diluent and antihypertensive effective compound of the formula ##STR13## wherein R.sub.1 is hydrogen or alkyl containing 1 to 3 carbon atoms;
- R.sub.2 is halogen;
- and
- R.sub.3 is halogen or --CF.sub.3
- or a pharmaceutically acceptable salt thereof.
A pharmaceutical composition for inhibiting xanthine oxidase comprising an inert pharmaceutically acceptable diluent and a xanthine oxidase inhibiting amount of compound of the formula ##STR14## wherein R.sub.1 is hydrogen or alkyl containing 1 to 3 carbon atoms;
- R.sub.2 is halogen;
- and
- R.sub.3 is halogen or --CF.sub.3
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.