Immuno-suppressive agents
OwnerJohn Williamsinventor
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Abstract
A method of providing an immuno-suppressive effect in the control or prophylaxis of neurological disorders, such as multiple sclerosis, and in organ and tissue transplants comprising administering a daily dosage of 5mg to 3g of .gamma.-linolenic or dihomo-.gamma.-linolenic acid or a functional derivative thereof, optionally together with a daily dosage of 25mg to 3g of linoleic acid or a functional derivative thereof. An oil extract from seeds of Oenothera biennis L. is a convenient source of .gamma.-linolenic acid and linoleic acid.
Claims8
A method of providing an immuno-suppressive effect in a patient suffering from multiple sclerosis which comprises administering to said patient a daily dosage of from 25mg to 3g of at least one compound selected from the group consisting of .gamma.-linolenic acid, dihomo-.gamma.-linolenic acid, C.sub.1 -C.sub.4 alkyl esters of .gamma.-linolenic and dihomo-.gamma.-linolenic acids and glyceride esters of .gamma.-linolenic and dihomo-.gamma.-linolenic acids.
A method of providing an immuno-suppressive effect in a patient suffering from multiple sclerosis which comprises administering to said patient a daily dosage of from 25mg to 3g of at least one compound selected from the group consisting of .gamma.-linolenic acid, dihomo-.gamma.-linolenic acid, C.sub.1 -C.sub.4 alkyl esters of .gamma.-linolenic and dihomo-.gamma.-linolenic acids and glyceride esters of .gamma.-linolenic and dihomo-.gamma.-linolenic acids, together with a daily dosage of from 5mg to 3g of linoleic acid, C.sub.1 -C.sub.4 alkyl esters or glyceride esters thereof.
Dependencies are inferred from the claim text.