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US 4,058,534 AGranted
Therapeutically effective nicotinates and N-oxide nicotinates of aliphatic amines
AssigneeSolco Basel AG
InventorsKarl-Heinz Jaeger, Willy Herbrand, deceased
Life of this patent
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Abstract
Aliphatic amine nicotinates (I) and N-oxide nicotinates (II) of the formulae ##STR1## have advantageous therapeutic properties, particularly for dilating blood vessels.
Claims3
A nicotinate N-oxide salt having the following structure ##STR4## wherein R is hydrogen, or a hydroxyl or thiol group, R.sub.1 is hydrogen or a C.sub.1 or C.sub.2 alkyl group, and n is a whole number from 1 to 4.
A compound of claim 1, 6-methyl-6-hydroxy-2-amino-heptane-N-oxide nicotinate.
A compound of claim 1, 6-methyl-2-amino-heptane-N-oxide nicotinate.
Dependencies are inferred from the claim text.