Horizontal flow-through coil planet centrifuge without rotating seals
AssigneeThe United States of America as represented by the Department of Health, Education and Welfare
InventorYoichiro Ito
Life of this patent
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Abstract
An apparatus for countercurrent chromatography consisting of a horizontal helical column array which is rotated about its own axis and simultaneously is rotated around a stationary central horizontal pipe at the same angular velocity to prevent twisting of its inlet and outlet flow tubes, which extend through the stationary central horizontal pipe. The column array is parallel to the stationary central pipe. The planetary motion allows both gravity and centrifugal force acting at respective times to provide high efficiency analytical and preparative scale separations on a broad spectrum of two-phase systems.
Claims10
In an apparatus for continuous countercurrent chromatography, a support, helical separation column means horizontally and rotatably mounted on the support, inlet and outlet flow tubes connected to said column means, fixed, elongated tube guide means on the support extending horizontally substantially parallel to and spaced from said column means and receiving said flow tubes at one end and defining a protective housing for the flow tubes, and means to simultaneously rotate said column means around its rotational axis and revolve said column means around the tube guide means at relative rates avoiding twisting of the flow tubes, whereby to simultaneously develop both gravitational force reversals and centrifugal forces in said column means.
In an apparatus for continuous countercurrent chromatography, a support, a conduit member horizontally rigidly mounted on said support, a pair of spaced parallel arm members, means rotatably supporting said arm members on said conduit member perpendicularly thereto, helical horizontal separation column means journalled between said arm members in spaced parallel relation to said conduit member, inlet and outlet flow tubes extending through said conduit member and being connected to said column means to define a flow path therethrough, and means to simultaneously rotate said column means around its rotational axis relative to said arm members and to revolve said arm members around said conduit member at relative rates avoiding twisting of the flow tubes, whereby to simultaneously develop gravitational force reversals in the column means caused by rotation of the column means relative to said arm members as well as the gravitational and centrifugal force effects caused by the revolution of said column means around said conduit member.
Dependencies are inferred from the claim text.