5,6,7,8:Tetrahydrocarbazole-1-carboxylic acid derivatives

Abstract

Carbazoles of the formula ##STR1## wherein R.sub.1 is hydroxymethyl, alkanoyloxymethyl, tetrazolyl, cyano, oximinocarbonyl, aminocarbonyl, carboxyl and salts thereof with physiologically acceptable bases and the esters thereof with physiologically acceptable alcohols and amides thereof with physiologically acceptable amines, R.sub.2 through R.sub.6 each are a hydrogen atom, halogen atom, lower alkyl, trifluoromethyl, or lower alkoxy, or R.sub.5 and R.sub.6 collectively are a five- or six-membered isocyclic ring, and R.sub.7 is a hydrocarbon of 3-8 carbon atoms or, when at least one of the R.sub.2 through R.sub.6 is other than a hydrogen atom, a hydrogen atom, methyl or ethyl, And the corresponding compounds wherein R.sub.7 is a hydrogen atom, methyl or ethyl, And the 5,6,7,8-tetrahydrocarbazoles, possess topical anti-inflammatory activity.

Dependencies are inferred from the claim text.