D-Homo-19-norsteroids
AssigneeHoffmann-La Roche Inc.
InventorsAndor Furst, Jurg Gutzwiller, Marcel Muller, Rudolf Wiechert, Ulrich Eder, Gunter Neef
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AssigneeHoffmann-La Roche Inc.
InventorsAndor Furst, Jurg Gutzwiller, Marcel Muller, Rudolf Wiechert, Ulrich Eder, Gunter Neef
Estimating the term…
D-homosteroids of the formula ##STR1## WHEREIN R.sup.3.alpha. is hydrogen, R.sup.3.beta. is hydroxy, lower alkanoyloxy or aroyloxy and R.sup.3.alpha. and R.sup.3.beta. taken together are oxo; R.sup.17a.alpha. is hydrogen, lower alkyl, ethynyl, vinyl, allyl, methallyl, propadienyl, 1-propynyl, butadiynyl or chloroethynyl; R.sup.17a.beta. is hydrogen, alkanoyl, aroyl, lower alkyl, cycloalkyl-lower-alkyl, benzyl, furfuryl or tetrahydropyranyl; R.sup.18 is hydrogen or methyl and the dotted line in the C-ring denotes an additional carbon to carbon bond in the 11,12-position and Processes for the preparation thereof are disclosed. The D-homosteroids of the present invention are useful as ovulation inhibitors and androgenic/anabolic agents.
A compound of the formula ##STR10## wherein R.sup.3.alpha. is hydrogen, R.sup.3.beta. is hydroxy, lower alkanoyloxy or aroyloxy and R.sup.3.alpha. and R.sup.3.beta. taken together are oxo;
Dependencies are inferred from the claim text.