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US 4,056,676 AGranted
Halogenated phenylthioacetamido cephalosporins
AssigneeEli Lilly and Company
InventorGeorge W. Huffman
Life of this patent
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Abstract
Certain halogenated phenylthioacetamido cephalosporanic acids and derivatives thereof, e.g., 7-[2'-(2",5"-dichlorophenylthio)acetamido]cephalosporanic acid, are effective antibiotics against Staphylococcus aureus cultures which show heterogeneous resistance to methicillin.
Claims5
A cephalosporin antibiotic compound of the formula ##STR8## in which R' is hydrogen, dicyclohexylamine, or a pharmaceutically acceptable cation;
- R is selected from the group consisting of hydrogen, C.sub.1 to C.sub.4 -alkanoyloxy, and N-pyridino;
- and X and Y are chlorine and are in the 3,4-, the 3,5-, or the 2,5-positons.
Dependencies are inferred from the claim text.