Hydrogels and articles made therefrom
AssigneeCorneal Sciences, Inc.
InventorsWilliam L. Mancini, Donald R. Korb, Miguel F. Refojo
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Abstract
This invention relates to polymers and hydrogels of polymers formed from a hydrophilic monomer of the group of dihydroxyalkyl acrylates and methacrylates, a substantially water insoluble monomer from the group of alkyl acrylates and methacrylates and preferably a minor amount of a water insoluble epoxidized alkyl acrylate or methacrylate. The hydrogels are preferably used for the formation of contact lenses, but may also be used for drug and pesticides delivery devices: dialysis, ultrafiltration and reverse osmosis membranes; implants in surgery and dentistry, and the like.
Claims29
A polymer formed by a free radical, bulk polymerization of a first hydrophilic monomer conforming to the formula:
- ##STR4## where R is hydrogen or methyl or methyl and n is a whole integer having a value of from 0 to 4,
- a second substantially water insoluble monomer conforming to the formula:
- ##STR5## where R is as above described and R' is alkyl having from 1 to 6 carbon atoms,
- the mole ratio of said first monomer to said second monomer varying between 1:3 and 20:1, and
- a third substantially water insoluble monomer conforming to the formula ##STR6## where R and n are as above defined, the concentration of said third monomer varying between 0 and 30% by weight of the first monomer,
- said polymer being insoluble in a member selected from the group of acetone, dioxane and mixtures thereof.
The shaped article of claim 30 in the form of a contact lens.
Dependencies are inferred from the claim text.