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US 4,055,718 AGranted
9-(2-O-Acyl-.beta.-D-arabinofuranosyl)-adenine compounds and method for their production
AssigneeParke, Davis & Company
InventorDavid Clarkston Baker
Life of this patent
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Abstract
9-(2-O-Acyl-.beta.-D-arabinofuranosyl)adenine compounds and their production by enzymatic removal of the 3-O-acyl and 5-O-acyl groups of a 9-(2,3-di-O-acyl-.beta.-D-arabinofuranosyl)adenine compound or a 9-(2,3,5-tri-O-acyl-.beta.-D-arabinofuranosyl)adenine compound. The monoester compounds are useful as antiviral agents. The compounds are watersoluble and lipophilic, thereby being adaptable to a wide variety of pharmaceutical formulations.
Claims4
A 9-(2-O-acyl-.beta.-D-arabinofuranosyl)adenine compound having the formula ##STR3## where R is a C.sub.2-4 straight chain or C.sub.3-4 branched chain alkanoyl group.
Dependencies are inferred from the claim text.