US 4,055,650 A · Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines

Abstract

This invention relates to new derivatives of pyridine having hypo-uricemic or hypolipemic properties. The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which X represents an oxy or thio group, R.sub.1 represents hydrogen, a group of the formula R.sub.3 NHCO (II), wherein R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, cycloalkyl or possibly substituted phenyl group, or a group of the formula R.sub.4 --CO (III) in which R.sub.4 represents a C.sub.1- C.sub.4 -alkyl group or a possibly substituted phenyl group, and R', R" and R'" represent each a possible substituent selected from the group comprising the halogens, the trifluoromethyl and the C.sub.1- C.sub.4 alkyl groups.

Claims6

Dependent claims

A compound of the following structure:

##STR8## in which X represents an oxy or thio group;
R.sub.1 represetns a group of the formula:
##STR9## wherein R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, cyclohexyl, unsubstituted phenyl or substituted phenyl group, or R.sub.1 represents a group of the formula:
R.sub.4 CO (III)
wherein R.sub.4 represents a C.sub.1 -C.sub.4 -alkyl group or an unsubstituted or substituted phenyl group;
R', R" and R'" represent each hydrogen or a substituent selected from the group comprising the halogen atoms, the trifluoromethyl group and the C.sub.1 -C.sub.4 -alkyl groups, as well as the pyridine N-oxide of the compounds of Formula I and the pharmaceutically acceptable base and acid addition salts of said compounds.

3 more elements

Dependencies are inferred from the claim text.

Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines

Life of this patent

Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines

Life of this patent

Abstract

Claims6