Fibrinolytic compositions
AssigneeBeecham Group Limited
InventorsJoseph Green, Michael Anthony Cawthorne
Life of this patent
Estimating the term…
Abstract
Fibrinolytic pharmaceutical compositions are provided in unit dosage form and comprise a water-soluble complex of a proteolytic enzyme linked covalently to a polymeric substance.
Claims9
A fibrinolytic pharmaceutical composition in unit dosage form suitable for administration by injection to humans which comprises an amount of a water soluble complex of a proteolytic enzyme sufficient to achieve the desired degree of fibrinolysis on administration to a human and linked covalently to a water-soluble polymeric substance having a molecular weight of from 10,000 to 500,000, said enzyme and said polymeric substance being present in the ratio of 1:2 to 1:50 said composition being substantially free of unreacted enzyme.
Dependencies are inferred from the claim text.