Derivatives of aminomethylcyclohexanecarboxylic acid
AssigneeRorer Italiana S.p.A.
InventorAldo Bertelli
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Abstract
The present invention is concerned with new derivatives of transaminomethylcyclohexanecarboxylic acid, which possess an anti-toxic, anti-hyperlipidic, anti-atherosclerosis, anti-phlogistic and gastroprotective activity. The compounds of the invention are represented by the general formula : ##STR1## in which : R is a group C.sub.n H.sub.2n+n' --CO-- n is an integer from 4 to 20, n' is +1, -1, -3 or -5, and R' is hydrogen or an alkyl group having 1 to 6 carbon atoms.
Claims10
A compound selected from the compounds of general formula:
- ##STR6## in which:
- R is in a group C.sub.n H.sub.2n+n,--CO--;
- n is an integer from 4 to 20,
- n' is selected from +1, -1, -3 and -5, and
- R is selected from hydrogen and the alkyl groups having 1 to 6 carbon atoms,
- and the inorganic and organic therapeutically acceptable salts thereof.
N-linoleyl-N-aminomethylcyclohexanecarboxylic acid and its therapeutically acceptable salts.
N-decanoyl-N-aminomethylcyclohexanecarboxylic acid and its therapeutically acceptable salts.
N-oleyl-N-aminomethylcyclohexanecarboxylic acid and its therapeutically acceptable salts.
N-linolenyl-N-aminocyclohexanecarboxylic acid and its therapeutically acceptable salts.
N-arachidoneyl-N-aminomethylcyclohexanecarboxylic acid and its therapeutically acceptable salts.
N-pentanoyl-N-aminomethylcyclohexanecarboxylic acid and its therapeutically acceptable salts.
N-hexanoyl-N-aminomethylcyclohexanecarboxylic acid and its therapeutically acceptable salts.
N-prostanoyl-aminomethylcyclohexanecarboxylic acid and its therapeutically acceptable salts.
Dependencies are inferred from the claim text.