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US 4,055,566 AGranted
5-Substituted-6H[1]-benzopyrano[3,2-c][1,8]naphthyridine-6,7-(6H)-diones
AssigneeSandoz Ltd.
InventorsGoetz E. Hardtmann, Gary M. Coppola
Life of this patent
Estimating the term…
Abstract
Anti-inflammatory agents of the formula: ##STR1## wherein R is lower alkyl, lower alkenyl, lower alkynyl, benzyl, alkyl or halo-substituted benzyl or cycloalkylalkyl, X is CH or N, R' is hydrogen, halo, lower alkyl or lower alkoxy when X is CH and hydrogen and alkyl when X is N, and R" is hydrogen or lower alkyl.
Claims11
A compound of the formula:
- ##STR9## wherein R is alkyl of 1 to 5 carbon atoms, alkenyl of 3 to 5 carbon atoms, alkynyl of 3 to 5 carbons, benzyl optionally mono- or disubstituted independently by fluoro, chloro or alkyl of 1 to 4 carbon atoms or cycloalkylalkyl in which the cycloalkyl is of 3 to 6 carbon atoms and the alkyl is of 1 to 3 carbon atoms, provided that the unsaturation on any alkenyl or alkynyl is other than on the alpha carbon atom,
- X is N,
- R' is hydrogen, alkyl of 1 to 4 carbon atoms, fluoro, chloro, bromo or alkoxy of 1 to 4 carbon atoms when X is CH and hydrogen or alkyl of 1 to 4 carbon atoms when X is N, and
- R" is hydrogen or alkyl of 1 to 4 carbon atoms.
1 more element
Dependencies are inferred from the claim text.