US 4,054,740 A · Hydroxybiotin

Abstract

This invention relates to a synthesis of biotin by the reduction of dehydrobiotin. The dehydrobiotin is prepared from 6-hydroxy-7-nitro-heptanoic acid methyl ester. Novel intermediates are also obtained by this synthesis.

Claims3

Dependent claims

A compound of the formula:

##STR21## wherein R.sub.1 is lower alkoxy, hydroxy, lower alkyl substituted or unsubstituted amino;
the racemates and optical antipodes thereof.

Dependencies are inferred from the claim text.

Facts

Application

05/610,707Filed 5 Sep 1975 · continuation in part

Priority

24 Dec 1974

Granted

18 Oct 1977

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07D 495/04
In which the condensed system contains two hetero rings: ortho-condensed systems
C07C 205/50
The carbon skeleton being further substituted by carboxyl groups: having nitro groups and carboxyl groups bound to acyclic carbon atoms of the…
C07C 323/00
Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms
C07D 333/42
With hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals,…:…

Hydroxybiotin

Life of this patent

Abstract

Claims3

Hydroxybiotin

Life of this patent

Abstract

Claims3