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AssigneeSankyo Company, Limited
InventorsYasuhiro Morisawa, Mitsuru Kataoka, Noritoshi Kitano, Toshiaki Matsuzawa
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Pyridine derivatives having the formula ##STR1## wherein R.sub.1 is an alkyl group having 1 to 3 carbon atoms; R.sub.2 is hydrogen atom or an alkyl group having 1 to 3 carbon atoms; R.sub.3 is hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 3 or 4 carbon atoms, an alkyl group having 1 or 2 carbon atoms and hydroxy as a substituent, an alkanoyl group having 1 to 18 carbon atoms, an alkenoyl group having 3 to 11 carbon atoms, an aromatic acyl group having 6 or 10 carbon atoms in the aromatic ring and optionally alkyl, alkoxy, acetylamino, cyano or halogen as a substituent, a heterocyclic acyl group, an alkylcarbamoyl group having 1 to 4 carbon atoms in the alkyl moiety, an allylcarbamoyl group or hydroxy group; n is an integer of 0 to 2 inclusive; and, when n is 2, R.sub.1 's may be the same or different; provided that when R.sub.2 is said alkyl group having 1 to 3 carbon atoms, R.sub.3 is said alkyl group having 1 to 4 carbon atoms. They are highly effective in the treatment of coccidiosis.
A compound having the formula ##STR7## wherein R.sub.1 is an alkyl group having 1 to 3 carbon atoms;
2-Nitroisonicotinamide.
N-Methyl 2-Nitroisonicotinamide.
N-Ethyl 2-Nitroisonicotinamide.
N-Hydroxymethyl 2-Nitroisonicotinamide.
N,N-Dimethyl 2-Nitroisonicotinamide
N-Ethyl-N-methyl 2-Nitroisonicotinamide.
6-Methyl-2-nitroisonicotinamide.
N-Ethyl 6-Methyl-2-nitroisonicotinamide.
N,N-Dimethyl 6-Methyl-2-nitroisonicotinamide.
3-Methyl-2-nitroisonicotinamide.
4-Methyl-6-nitronicotinamide.
4-Methyl-6-nitro-2-pyridinecarboxamide.
N,N-Diethyl 6-Methyl-2-nitroisonicotinamide.
An anticoccidial composition containing an amount, sufficient to inhibit coccidiosis, of a compound having the formula ##STR10## intimately dispersed in an inert carrier, wherein R.sub.1 is an alkyl group having 1 to 3 carbon atoms;
A poultry feed having dispersed therein for control of poultry coccidiosis at least 0.005% by weight of a compound having the formula ##STR13## wherein R.sub.1 is an alkyl group having 1 to 3 carbon atoms;
Dependencies are inferred from the claim text.