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US 4,054,660 AGranted
Method of inhibiting prolactin
AssigneeEli Lilly and Company
InventorsJames A. Clemens, Edmund C. Kornfeld, Nicholas J. Bach
Life of this patent
Estimating the term…
Abstract
D-2-halo-6-alkyl-8-substituted ergolines and related compounds are inhibitors of prolactin in mammals.
Claims2
A process for inhibiting the secretion of prolactin in mammals which comprises administering from 0.01 to 10 mg/kg/day of mammalian weight of a compound of Formula II or a salt thereof formed with a pharmaceutically-acceptable acid, to a mammal having a condition in which there is an excess of prolactin being secreted:
- ##STR5## wherein X is Cl, Br or I, R is CH.sub.2 --CN or ##STR6## and R' is C.sub.1 -C.sub.3 primary alkyl.
Dependencies are inferred from the claim text.